The MP-SPR Navi™ 420A ILVES excels in molecular interaction studies, particularly with small molecules, proteins, lipids, and nanoparticles. Its design prioritizes minimal dead volume and high sensitivity, ensuring accurate measurements. With four liquid channels, it offers efficient, parallel analysis. This instrument is perfectly suited for exploring molecular interactions, delving into biophysical phenomena, and conducting live cell studies. The ILVES's optimized fluidics and sensitive detection make it a powerful tool for researchers seeking detailed insights into complex biological processes. Its ability to handle diverse sample types makes it versatile for a wide range of applications.
Features:
- 4 fluidic channels for high throughput
- Automation of samples from 96 and 384 well plates allows for unattended runs
- Measurements of kinetic constants, concentration and competition analysis, affinity and EC50
- KineticTitration for faster interaction affinity and kinetic measurements
- Exceptionally wide angular range 40˚ – 78˚ enables measurements of small organic molecules and large proteins, but also metallic nanoparticles and live cells. Most importantly, it enables in-line bulk effect separation - PureKinetics™
- Two independent wavelength measurements from each fluidic channel, enabling the detection of thickness and refractive index or conformational changes
- Controlled buffer flow conditions with precise syringe pumps and integrated degasser
- Software switch for serial and individual injections
- Partial loop injections allowing minimized sample consumption
- Complete software package for convenient control of the instrument and easy analysis of the results. 420A ILVES instrument comes with both TraceDrawer™ for MP-SPR Navi™ and MP-SPR Navi™ LayerSolver software. LayerSolver is an advantageous software to determine thickness and RI from multiple wavelength measurements whereas Trace Drawer™ is a powerful software for the determination of affinity and kinetic constants
- MP-SPR Navi™ instruments utilize optical RI matching elastomer and therefore, sensors are very easy to exchange and remove for further analysis with other methods such as AFM or microscopy