The MP-SPR Navi™ 400 KONTIO, a 4-channel instrument, is specifically designed for cell adhesion and cell-based interaction studies under physiologically relevant conditions. This system allows for simultaneous, multi-channel analysis, providing detailed insights into cellular dynamics. Its unique design enables researchers to mimic in vivo environments, fostering more accurate and relevant data. Ideal for exploring living cell behavior and intricate molecular interactions, the KONTIO facilitates advanced research in fields such as cell biology, immunology, and drug discovery. The instrument's capabilities make it a valuable tool for understanding complex biological processes at the cellular level.
Features:
- 4 fluidic channels for simultaneous measurements
- Two independent wavelength measurements from each fluidic channel, enabling detection of thickness and refractive index, conformational changes and cellular interactions
- Exceptionally wide angular range 40˚ – 78˚C enables measurements with complex cell culture media and other crude samples like serum and saliva. Cells can be directly cultured on the sensor slide surface or the sensor surface is modified and cells are introduced as a sample
- Controlled liquid flow conditions with peristaltic pump
- Manual filling of injection loops required
- Parallel or serial injections into fluidic channels
- 400 KONTIO is provided with a basic software package of MP-SPR Navi™ Control and DataViewer for convenient control of the instrument and basic analysis of the results. Advanced analysis modules are optional: MP-SPR Navi™ LayerSolver™ to determine thickness and refractive index from multiple wavelength measurements and TraceDrawer™ for MP-SPR Navi™ a powerful software for determination of affinity and kinetic constants and more
- MP-SPR Navi™ instruments utilize optical RI matching elastomer and therefore sensors are very easy to exchange. They can also be further analyzed with other methods, such as AFM or microscopy
- Open design enables convenient access to the easily removable flow-cell, as well as to tubing, pump and injection valves
- The instrument enables attachment of a separate autosampler, pump, degasser or even own microfluidic sample pre-processing cartridge