Pulsed-field electrophoresis with the Rotaphor system allows the separation of DNA beyond the 50 kb limit of conventional agarose electrophoresis. Thanks to the patented electrode rotor, the electrical field can be applied in virtually any angle and all common techniques for separation of large DNA molecules can be applied. This includes methods like CHEF, FIGE, PAGE, and naturally ROFE (Rotating Field Electrophoresis).