Suppressed oxygen environment provides control in stem cell differentiation to maintain full pluripotency of cell lines.
- O2 Range: 0.5 to 21%
- O2 Accuracy: ± 0.25%
Relative Humidity (RH) Control
An RH sensor continuously samples chamber humidity levels to monitor
and control the humidity set point. If the system senses any variation
in humidity, vapour is injected into the chamber by a water reservoir
located underneath the chamber.
Dual Sterilisation Cycles
Easily accessible through the NuTouch Intelligent Interface,
In-VitroCell incubators offer 145°C high heat sterilisation and a 95°C
humidified decontamination cycles as a preventative measure and to
eradicate contamination in the growth chamber. On-screen instructions
direct users through the process. A timer function is available to delay
the sterilisation process for an overnight procedure.
NuTouch Intelligent Interface
NuTouch is a user-friendly 5” x 7” (127 x 178 mm) colour touch screen
designed for high user adoption. The electronic control system is a
microcomputer designed to service the precise control requirement of the
chamber environment for culture growth. The microcomputer is supported
with Read-Only Memory (ROM) containing executable software, Random
Access Memory (RAM) for temporary storage, and Electronically Erasable
Programmable Read Only Memory (EEPROM) for control set points and
parameters. The EEPROM provides for indefinite storage of these values
during periods of power off or power interruption (power fault
tolerant).
NuTouch features are:
- Temperature and Gas Monitor and Control
- Status Indicators – Screen Identity; Run or Standby mode; Door Adjar; Air and CO2 Inject; Air and CO2 Chamber Sampling
- Date and Time Functions in International Format
- Password Protection
- On-screen Icon Descriptions – Pressing on any icon will provide a description of what the item is
- On-screen Directions – Directions are available to perform calibrations
- Step-by-Step directions (i.e. sterilisation cycle procedure)
- Alarm Status Menu - A red “Alarm Status” text button will appear on
the Main Screen to indicate a fault within the Incubator system
- Maintenance Required Reminders – On-screen Icon "MAINTENANCE
REQUIRED" appears when a programmable reminder (0 to 48 months) hits set
point to notify filter check
- Historical Performance Monitor – Temperature and CO2 gas
history is available to view on screen in graphical form or can be
downloaded via USB for alarms, control systems, events, and performance
information
- Service Settings and Complete Diagnostic Controls
- System Information
- Display Settings
Constant Contamination Control (C3)
The NU-5841 offers a unique blend of product features to promote cell
growth while minimising potential contamination, creating the most
intrinsic and reliable growth chamber.
Closed Loop HEPA Filtration
A maintenance-free air pump continuously draws environmental samples
from two locations inside the chamber and passes the sample through a
99.99% HEPA filter before entering the sensor bay to measure gas and
oxygen levels. The sensor bay measures gas and humidity levels from the
sample to monitor before injecting back into the growth chamber. The
NuTouch Electronic Control system will then determine the appropriate
course of action to maintain chamber set-point conditions by placing the
system on standby or injecting 99.99% HEPA filtered CO2 gas, air, nitrogen, or vapour into the growth environment.
ISO Class 5 Cleanroom Conditions
Based on clean room technology, the NU-5841 maintains the growth
chamber at a positive pressure, similar to an ISO Class 5 Cleanroom, to
slow airflow to minimise desiccation. Anytime the chamber door is open
to the laboratory environment, clean HEPA filtered will be forced out
instead of contaminated lab air being drawn in.
Single Beam, Dual Wave Infrared (IR) Sensor
A microprocessor-based, non-dispersive, single source dual wave infrared (IR) sensor monitors and controls CO2 levels inside the growth chamber. Wavelengths are only absorbed by CO2 making
measurement insensitive to other components, such as water vapour. The
stable IR sensor has a controlled range of 0.1 to 20% accurate within
0.1%.
Temperature Uniformity
The chamber walls are surrounded by five heating elements to control
temperature. A door heater is separately controlled to minimise
condensation on the inner chamber door. The heating elements are wrapped
in a high density R5 insulation to maintain temperature integrity. Dual
temperature sensor probes monitor and control temperature set points to
ensure consistency and uniformity throughout the chamber.
Incubator Humidity
A relative humidity level of up to 90% is achieved in the Incubator
by the use of a stainless steel pan placed on the bottom of the chamber.
An air pump injects fresh air into the chamber at a preset duty cycle
to reduce condensation forming on the chamber walls and front glass
door.
Advanced Construction
The inner chamber is constructed of high grade polished stainless
steel using crevice-free construction that provides an easily cleanable
inert surface that does not promote biological growth. Seamless coved
interior corners are easily cleaned promoting a healthy growth chamber. A
single piece gasket creates a liquid tight seal from incubator chamber
to inner door to eliminate condensation build up and potential
contamination. The inner chamber shelving and gasket may be removed and
routinely autoclaved if desired.
Minimal Vibration Promotes Cell Growth
By minimising moving parts, the NU-5841 utilises an accurate air pump to inject air and gas to eliminate potential vibration.
A Smaller Footprint with More Useable Space
A large 7 cubic foot (200 Litre) growth chamber comes standard with
four incubator shelves with a maximum capacity of 23 shelves. By
attaching heating elements directly to the chamber and insulating with
High Density R5 insulation, the NU-5841 was engineered as a compact
design while maximising chamber capacity.
Optional Features
Add CuVerro® Antimicrobial Copper Surfaces to the incubator growth
chamber and shelving to kill bacteria* and minimise potential incubator
contamination. CuVerro® is laboratory tested and EPA
registered. Laboratory testing shows that CuVerro Antimicrobial Copper
Surfaces kill more than 99.99% of bacteria within 2 hours of exposure,
and continues to kill 99% of bacteria even after repeated contamination
when regularly cleaned including;
- MRSA
- Staphylococcus Aureus
- Enterobacter Aerogenes
- Pseudomonas Aeruginosa
- E coli